On Sulphur-containing Amino-acids. V

The biochemistry and pharmacology of excitatory sulphur-containing amino acids.

1,-Glutamate is now well established as the predominant transmitter at fast-acting excitatory synapses in the mammalian central nervous system. Other amino acids such as L-aspartate and several acidic sulphur-containing amino acids (SAAs) which exhibit potent depolarizing actions similar to that of Lglutamate [I-31 are known to exist in the brain and/or are present in the brain under pathologic...

Effect of aliphatic, monocarboxylic, dicarboxylic, heterocyclic and sulphur-containing amino acids on Leishmania spp. chemotaxis.

In the sand-fly mid gut, Leishmania promastigotes are exposed to acute changes in nutrients, e.g. amino acids (AAs). These metabolites are the main energy sources for the parasite, crucial for its differentiation and motility. We analysed the migratory behaviour and morphological changes produced by aliphatic, monocarboxylic, dicarboxylic, heterocyclic and sulphur-containing AAs in Leishmania a...

Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysis.

1. Plasma sulphur-containing amino acids were measured in 19 patients with renal failure on chronic haemodialysis and in 22 normal subjects, to determine the rate of accumulation of these amino acids in chronic azotaemia. 2. Cysteine--homocysteine mixed disulphide was significantly increased in patients before dialysis and homocysteine was detected in low concentration in 10 patients. Cystine a...

Response of layers fed on diets dificient in protein and sulphur amino acids supplemented with lipid

Thermodynamic Study Of Acid Catalysed Oxidation Of Sulphur Containing Amino Acids By Oxo (Salen) Chromium (V) Ion

The kinetics and thermodynamics of oxidation of Methionine and Ethionine by oxo (salen) chromium (V) ion have been investigated by spectrophotometric method in aqueous medium. The presence of water facilitates ligation of water to the Cr centre and forms an active oxidant [H2O (salen) Cr=O] + .The reaction is found to be first order each in the oxidant and the substrate. The presence of H + ion...